Terminated

Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo

This study has been terminated and is no longer seeking study volunteers.

WHAT IS THE PURPOSE OF THIS STUDY?

The purpose of this study is to determine if an investigational treatment is effective compared with placebo in the treatment of adults and children with adenoviral conjunctivitis.

TRIAL AT A GLANCE

Condition

Adenoviral Conjunctivitis

Study Intervention

SHP640; Placebo

Possibility of Active Treatment

50%

Study Type

Interventional

Phase

Phase 3

IS THIS STUDY RIGHT FOR ME?

AGE

N/A

N/A

GENDERS

ACCEPTS HEALTHY VOLUNTEERS

No

PARTICIPATION DURATION/ REQUIREMENTS

Participation will consist of up to 5 visits to the study site over a period of up to 15 days. Enrolled patients will be randomly assigned to receive either the investigational treatment or placebo in a ratio of 1:1. Multiple patients from the same household will be eligible to participate in the study (up to a prespecified household cap). Patients from the same household will be assigned to the same treatment group.Patients who are randomized into the trial will receive the first dose of the assigned treatment on Day 1. All following doses will be administered by the patient or caregiver in both eyes 4 times per day for 7 days.

ENTRY CRITERIA

Must test positive for adenoviral conjunctivitis in at least 1 eye (via the RPS AdenoPlus® test at Visit 1)

Have a clinical diagnosis of suspected adenoviral conjunctivitis in at least 1 eye (thesame eye as the RPS AdenoPlus® positive eye)

Must be willing to discontinue contact lens wear for the duration of the study

Cannot have a known or suspected intolerance or hypersensitivity to the investigationalproduct, closely related compounds, or any of the stated ingredients

Cannot have previously enrolled in a FST-100 or SHP640 clinical study

Cannot have had ocular surgical intervention within ≤ 6 months prior to Visit 1 orplanned for the period of the study

Cannot have active or history of ocular herpes

Cannot have clinical signs of ocular allergy or an ocular infection (e.g., bacterial,acanthamoeba, fungal or other ocular viral infection) currently or within ≤ 30 days ofVisit 1 other than adenoviral conjunctivitis

Study Locations

Enter your city or postal code to find a location near you.

RESULTS

  • 1.

    Shire Call Center

    Lexington, MA
    United States of America

    miles

  • 2.

    Houston Eye Associates

    Houston, Texas
    United States of America

    miles

  • 3.

    Emanuelli Research & Development Center, LLC

    Arecibo, Puerto Rico
    Puerto Rico

    miles

  • 4.

    Bowden Eye & Associates

    Jacksonville, Florida
    United States of America

    miles

  • 5.

    Wohl Eye Center

    Bloomingdale, Illinois
    United States of America

    miles

  • 6.

    Fichte, Endl and Elmer Eyecare

    Niagara Falls, New York
    United States of America

    miles

  • 7.

    International Research Center

    Tampa, Florida
    United States of America

    miles

  • 8.

    Berrocal and Associates

    San Juan, Puerto Rico
    Puerto Rico

    miles

  • 9.

    Hull Eye Center

    Lancaster, California
    United States of America

    miles

  • 10.

    Medsol Clinical Research Center

    Port Charlotte, Florida
    United States of America

    miles

  • 11.

    Clark S Tsai Eye Center

    Concord, California
    United States of America

    miles

  • 12.

    Wolstan and Goldberg Eye Associates

    Torrance, California
    United States of America

    miles

  • 13.

    Chrysalis Clinical Research

    St. George, Utah
    United States of America

    miles

  • 14.

    University Of Puerto Rico, School of Medicine

    Carolina, Puerto Rico
    Puerto Rico

    miles

  • 15.

    Saltzer Medical Group

    Nampa, Idaho
    United States of America

    miles

  • 16.

    Specialty Eye Care

    Parker, Colorado
    United States of America

    miles

  • 17.

    East West Eye Institute

    Torrance, California
    United States of America

    miles

  • 18.

    The Eye Care Institute

    Louisville, Kentucky
    United States of America

    miles

  • 19.

    Danbury Eye Physicians and Surgeons

    Danbury, Connecticut
    United States of America

    miles

  • 20.

    Silverstein Eye Centers

    Kansas City, Missouri
    United States of America

    miles

  • 21.

    South Florida Research Center Inc.

    Miami, Florida
    United States of America

    miles

  • 22.

    Cleveland Eye Clinic

    Cleveland, Ohio
    United States of America

    miles

  • 23.

    Midwest Cornea Associates, LLC

    Indianapolis, Indiana
    United States of America

    miles

  • 24.

    Lugene Eye Institute Inc

    Glendale, California
    United States of America

    miles

  • 25.

    University of Southern California

    Los Angeles, California
    United States of America

    miles

  • 26.

    The Ohio State University

    Columbus, Ohio
    United States of America

    miles

  • 27.

    Eyeland Vision

    El Paso, Texas
    United States of America

    miles

  • 28.

    Washington University

    St.Louis, Missouri
    United States of America

    miles

  • 29.

    Jenkins Eye Care

    Honolulu, Hawaii
    United States of America

    miles

  • 30.

    Apex Eye Kenwood

    Cincinnati, Ohio
    United States of America

    miles

  • 31.

    Sun Research Institute, LLC

    San Antonio, Texas
    United States of America

    miles

  • 32.

    South Shore Eye Care

    Wantagh, New York
    United States of America

    miles

  • 33.

    Sabates Eye Centers

    Leawood, Kansas
    United States of America

    miles

  • 34.

    Piedmont Eye Center, Inc.

    Lynchburg, Virginia
    United States of America

    miles

  • 35.

    Philadelphia Eye Associates

    Philadelphia, Pennsylvania
    United States of America

    miles

  • 36.

    Bruce A. Segal, MD, PA

    Delray Beach, Florida
    United States of America

    miles

  • 37.

    Shettle Eye Research, Inc.

    Largo, Florida
    United States of America

    miles

  • 38.

    Jean Brown Research

    Salt Lake City, Utah
    United States of America

    miles

  • 39.

    North Valley Eye Medical Group Inc

    Mission Hills, California
    United States of America

    miles

  • 40.

    IPS Research Company

    Oklahoma City, Oklahoma
    United States of America

    miles

  • 41.

    Tekwani Vision Center

    St Louis, Missouri
    United States of America

    miles

  • 42.

    Wellish Vision Institute

    Las Vegas, Nevada
    United States of America

    miles

  • 43.

    West Coast Eye Care Associates

    San Diego, California
    United States of America

    miles

  • 44.

    The Eye Institute of Utah

    Salt Lake, Utah
    United States of America

    miles

  • 45.

    Physicians to Children & Adolescents

    Bardstown, Kentucky
    United States of America

    miles