Now Recruiting

Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo

WHAT IS THE PURPOSE OF THIS STUDY?

The purpose of this study is to determine if an investigational treatment is effective compared with placebo in the treatment of adults and children with adenoviral conjunctivitis.

TRIAL AT A GLANCE

Condition

Adenoviral Conjunctivitis

Study Intervention

SHP640; Placebo

Possibility of Active Treatment

50%

Study Type

Interventional

Phase

Phase 3

IS THIS STUDY RIGHT FOR ME?

AGE

N/A

N/A

GENDERS

ACCEPTS HEALTHY VOLUNTEERS

No

PARTICIPATION DURATION/ REQUIREMENTS

Participation will consist of up to 5 visits to the study site over a period of up to 13 days. Enrolled patients will be randomly assigned to receive either the investigational treatment or placebo in a ratio of 1:1. Multiple patients from the same household will be eligible to participate in the study (up to a prespecified household cap). Patients from the same household will be assigned to the same treatment group.Patients who are randomized into the trial will receive the first dose of the assigned treatment on Day 1. All following doses will be administered by the patient or caregiver in both eyes 4 times per day for 7 days.

ENTRY CRITERIA

Must test positive for adenoviral conjunctivitis in at least 1 eye (via the RPS AdenoPlus® test at Visit 1)

Have a clinical diagnosis of suspected adenoviral conjunctivitis in at least 1 eye (thesame eye as the RPS AdenoPlus® positive eye)

Must be willing to discontinue contact lens wear for the duration of the study

Cannot have a known or suspected intolerance or hypersensitivity to the investigationalproduct, closely related compounds, or any of the stated ingredients

Cannot have previously enrolled in a FST-100 or SHP640 clinical study

Cannot have had ocular surgical intervention within ≤ 6 months prior to Visit 1 orplanned for the period of the study

Cannot have active or history of ocular herpes

Cannot have clinical signs of ocular allergy or an ocular infection (e.g., bacterial,acanthamoeba, fungal or other ocular viral infection) currently or within ≤ 30 days ofVisit 1 other than adenoviral conjunctivitis

Study Locations

We are planning* on conducting this study in 2 countries around the world.

    • Puerto Rico
    • United States of America

Enter your city or postal code to find a location near you.

RESULTS

  • 1.

    Shire Call Center

    Lexington, MA
    United States of America

    +1 866 842 5335

    clinicaltransparency@shire.com

    miles

  • 2.

    Houston Eye Associates

    Houston, Texas
    United States of America

    832-553-7140

    cgonzales@houstoneye.com

    miles

  • 3.

    Emanuelli Research & Development Center, LLC

    Arecibo, Puerto Rico
    Puerto Rico

    (787) 879-7722

    aemanuelli@gmail.com

    miles

  • 4.

    Bowden Eye & Associates

    Jacksonville, Florida
    United States of America

    904-296-0098

    fbowden3@hotmail.com

    miles

  • 5.

    Wohl Eye Center

    Bloomingdale, Illinois
    United States of America

    6303512030

    lisa.wohl@dupagemd.com

    miles

  • 6.

    Fichte, Endl and Elmer Eyecare

    Niagara Falls, New York
    United States of America

    716-828-8970

    thomas.elmer@fichte.com

    miles

  • 7.

    International Research Center

    Tampa, Florida
    United States of America

    (813)875-6588

    benp@irctampa.com

    miles

  • 8.

    Berrocal and Associates

    San Juan, Puerto Rico
    Puerto Rico

    787-725-9315

    mariahberrocal@hotmail.com

    miles

  • 9.

    Hull Eye Center

    Lancaster, California
    United States of America

    (661) 945-4502

    jkim@hecresearch.com

    miles

  • 10.

    Medsol Clinical Research Center

    Port Charlotte, Florida
    United States of America

    (941) 623-9744

    dklein@medsolcrc.com

    miles

  • 11.

    Clark S Tsai Eye Center

    Concord, California
    United States of America

    (925)686-2020

    cst2010@yahoo.com

    miles

  • 12.

    Wolstan and Goldberg Eye Associates

    Torrance, California
    United States of America

    310-602-5640

    tstudy1@wgeye.com

    miles

  • 13.

    Chrysalis Clinical Research

    St. George, Utah
    United States of America

    435-656-1704

    jhendrix@sgccr.com

    miles

  • 14.

    University Of Puerto Rico, School of Medicine

    Carolina, Puerto Rico
    Puerto Rico

    (787) 701-1121

    enid.garcia3@upr.edu

    miles

  • 15.

    Saltzer Medical Group

    Nampa, Idaho
    United States of America

    208-463-327-7

    rsmckinnon@saltzermed.com

    miles

  • 16.

    Specialty Eye Care

    Parker, Colorado
    United States of America

    303-797-1499

    sjohnson@insightvisiongroup.com

    miles

  • 17.

    East West Eye Institute

    Torrance, California
    United States of America

    626-224-6658

    drliu@awakenyoureyes.com

    miles

  • 18.

    The Eye Care Institute

    Louisville, Kentucky
    United States of America

    502-589-1500

    drmeyer@eyecareinstitute.com

    miles

  • 19.

    Danbury Eye Physicians and Surgeons

    Danbury, Connecticut
    United States of America

    203-791-2020

    clinicaleye@danburyeye.com

    miles

  • 20.

    Silverstein Eye Centers

    Kansas City, Missouri
    United States of America

    816-595-3958

    ssilverstein@silversteineyecenters.com

    miles

  • 21.

    South Florida Research Center Inc.

    Miami, Florida
    United States of America

    305-456-3236

    obenitez@southflresearch.com

    miles

  • 22.

    Cleveland Eye Clinic

    Cleveland, Ohio
    United States of America

    216-503-6535

    drchester@clevelandeyeclinic.com

    miles

  • 23.

    Midwest Cornea Associates, LLC

    Indianapolis, Indiana
    United States of America

    317-805-4527

    rdeitchjr@aol.com

    miles

  • 24.

    Lugene Eye Institute Inc

    Glendale, California
    United States of America

    818-246-2560

    elharazi@lugeneeye.com

    miles

  • 25.

    University of Southern California

    Los Angeles, California
    United States of America

    323-865-6935

    charles.flowers@med.usc.edu

    miles

  • 26.

    The Ohio State University

    Columbus, Ohio
    United States of America

    614-688-1669

    fogt.78@osu.edu

    miles

  • 27.

    Eyeland Vision

    El Paso, Texas
    United States of America

    915-526-7418

    eyedocholt@gmail.com

    miles

  • 28.

    Washington University

    St.Louis, Missouri
    United States of America

    314-747-5832

    huangandrew@wustl.edu

    miles

  • 29.

    Jenkins Eye Care

    Honolulu, Hawaii
    United States of America

    808-777-4413

    tyrielee@gmail.com

    miles

  • 30.

    Apex Eye Kenwood

    Cincinnati, Ohio
    United States of America

    513-745-9787

    karen.klugo@apexeye.com

    miles

  • 31.

    Sun Research Institute, LLC

    San Antonio, Texas
    United States of America

    210-227-1289

    llothringer@sunresearch.com

    miles

  • 32.

    South Shore Eye Care

    Wantagh, New York
    United States of America

    516-785-3900

    jluchs@aol.com

    miles

  • 33.

    Sabates Eye Centers

    Leawood, Kansas
    United States of America

    913-671-3242

    macalusok@sabateseye.com

    miles

  • 34.

    Piedmont Eye Center, Inc.

    Lynchburg, Virginia
    United States of America

    434-947-3984

    paauwer@gmail.com

    miles

  • 35.

    Philadelphia Eye Associates

    Philadelphia, Pennsylvania
    United States of America

    215-339-8100

    crepke@comcast.net

    miles

  • 36.

    Bruce A. Segal, MD, PA

    Delray Beach, Florida
    United States of America

    973-886-4129

    segalmd@bellsouth.net

    miles

  • 37.

    Shettle Eye Research, Inc.

    Largo, Florida
    United States of America

    727-674-2500

    lshettle@tampabay.rr.com

    miles

  • 38.

    Jean Brown Research

    Salt Lake City, Utah
    United States of America

    801-424-3090

    eyestudyutah@gmail.com

    miles

  • 39.

    North Valley Eye Medical Group Inc

    Mission Hills, California
    United States of America

    818-365-0606

    rsmyth@ucla.edu

    miles

  • 40.

    IPS Research Company

    Oklahoma City, Oklahoma
    United States of America

    405-235-8188

    dsylvester@ipsresearch.com

    miles

  • 41.

    Tekwani Vision Center

    St Louis, Missouri
    United States of America

    314-842-2020

    tekwani_md@yahoo.com

    miles

  • 42.

    Wellish Vision Institute

    Las Vegas, Nevada
    United States of America

    702-932-4270

    klwellish@gmail.com

    miles

  • 43.

    West Coast Eye Care Associates

    San Diego, California
    United States of America

    b.k@westcoasteyecare.com

    miles

  • 44.

    The Eye Institute of Utah

    Salt Lake, Utah
    United States of America

    8012662283

    rcarter@theeyeinstitute.com

    miles

*Planning is an intent to conduct this study in the specified countries and is subject to change.